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KMID : 0359320210610010001
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Korean Journal of Veterinary Research
2021 Volume.61 No. 1 p.1 ~ p.1
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Successful management of systemic lupus erythematosus with levamisole in a Dachshund dog
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Kim Dong-Hyun
Han Hyun-Jung
Kim Jung-Hyun
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Abstract
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A 5-year-old neutered female Dachshund dog presented with a 3-month history of hyperthermia, skin lesions, and shifting lameness. Based on physical examination, blood tests, urinalysis, and radiographs, the dog was diagnosed with systemic lupus erythematosus. Clinical signs improved after administration of prednisolone and cyclosporine but relapsed after the prednisolone was reduced due to side effects. Oral levamisole was commenced and the other immunosuppressants were tapered over a period of 2 months and then stopped. Levamisole was retained as the sole therapy for an additional 2 months. Six months after discontinuation of all treatment, the patient remained in remission.
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KEYWORD
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autoimmune disease, levamisole, regulatory T-cells, systemic lupus erythematosus
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